Connectivity | 85 |
---|---|
Notes | Voltage-dependent Ca(2+) channels are multisubunit complexes found in the membrane of many excitable cells that regulate calcium entry (see MIM 601011). N-type calcium channels, which control neurotransmitter release from neurons, are dihydropyridine-insensitive and omega-conotoxin-sensitive. The alpha-1 subunit forms the pore through which calcium enters the cell, and is encoded by a family of at least 5 genes.[supplied by OMIM] |
Hugo ID | 1389 |
Name | CACNA1B |
Description | calcium channel, voltage-dependent, L type, alpha 1B subunit |
URN | urn:agi-llid:774 |
GO Cellular Component | integral to membrane |
---|---|
membrane | |
voltage-gated calcium channel complex |
Cell Localization | Plasma membrane |
---|
GO Biological Process | calcium ion transport |
---|---|
cation transport | |
ion transport | |
locomotory behavior | |
neurotransmitter secretion | |
regulation of blood pressure | |
regulation of heart rate | |
synaptic transmission |
Microarray ID | 1370444_at |
---|---|
1371175_a_at | |
AF055477_at | |
m92905_s_at | |
98360_at | |
1425812_a_at | |
U04999_s_at | |
Msa.202.0_at | |
A_51_P206573 | |
NM_007579 | |
M94172 | |
33960_s_at | |
207162_s_at | |
M94172_s_at | |
A_32_P153773 | |
I_2031539 | |
A_23_P159622 | |
I_964947 | |
A_23_P84849 | |
I_965232 |
MGI ID | 88296 |
---|
GO Molecular Function | voltage-gated ion channel activity |
---|---|
ion channel activity | |
cation channel activity | |
calcium channel activity | |
ATP binding | |
voltage-gated calcium channel activity | |
calcium ion binding |
GO ID | GO:0005244 |
---|---|
GO:0005216 | |
GO:0005261 | |
GO:0005262 | |
GO:0005524 | |
GO:0005245 | |
GO:0005509 | |
GO:0007626 | |
GO:0006812 | |
GO:0008016 | |
GO:0006811 | |
GO:0008217 | |
GO:0006816 | |
GO:0016020 | |
GO:0005891 | |
GO:0016021 | |
GO:0007268 |
Swiss-Prot Accession | Q00975 |
---|
Keyword | adrenoceptor |
---|
OMIM ID | OMIM:601012 |
---|
Alias | Cacna1b |
---|---|
calcium channel, voltage-dependent, N type, alpha 1B subunit | |
Cav2.2 | |
Cchn1a | |
calcium channel, voltage-dependent, L type, alpha 1B subunit | |
alpha(1B) | |
AW060892 | |
CACNN | |
calcium channel, N type | |
calcium channel, voltage-dependent, alpha 1B subunit, N type | |
Ca-alpha-1B | |
CACNL1A5 | |
4921522D01Rik | |
BIII | |
Brain calcium channel III | |
CACH5 | |
RIKEN cDNA 4921522D01 gene | |
Voltage-dependent N-type calcium channel alpha-1B subunit | |
Calcium channel, L type, alpha-1 polypeptide isoform 5 |
Organism | Rattus norvegicus |
---|---|
Mus musculus | |
Human |
LocusLink ID | 257648 |
---|---|
12287 | |
99299 | |
99310 | |
99436 | |
774 |
Source | ResNet |
---|
RGD ID | 628852 |
---|
Pathway | path |
---|---|
path2 | |
path1 | |
path3 | |
path4 | |
path5 | |
path6 | |
path7 | |
Copy of 'path8' | |
path8 | |
pathfeb |
Unigene ID | Rn.85880 |
---|---|
Mm.4424 | |
Hs.69949 |
Group | nucleotide binding |
---|---|
metal ion binding |