| Connectivity | 85 |
|---|---|
| Notes | Voltage-dependent Ca(2+) channels are multisubunit complexes found in the membrane of many excitable cells that regulate calcium entry (see MIM 601011). N-type calcium channels, which control neurotransmitter release from neurons, are dihydropyridine-insensitive and omega-conotoxin-sensitive. The alpha-1 subunit forms the pore through which calcium enters the cell, and is encoded by a family of at least 5 genes.[supplied by OMIM] |
| Hugo ID | 1389 |
| Name | CACNA1B |
| Description | calcium channel, voltage-dependent, L type, alpha 1B subunit |
| URN | urn:agi-llid:774 |
| GO Cellular Component | integral to membrane |
|---|---|
| membrane | |
| voltage-gated calcium channel complex |
| Cell Localization | Plasma membrane |
|---|
| GO Biological Process | calcium ion transport |
|---|---|
| cation transport | |
| ion transport | |
| locomotory behavior | |
| neurotransmitter secretion | |
| regulation of blood pressure | |
| regulation of heart rate | |
| synaptic transmission |
| Microarray ID | 1370444_at |
|---|---|
| 1371175_a_at | |
| AF055477_at | |
| m92905_s_at | |
| 98360_at | |
| 1425812_a_at | |
| U04999_s_at | |
| Msa.202.0_at | |
| A_51_P206573 | |
| NM_007579 | |
| M94172 | |
| 33960_s_at | |
| 207162_s_at | |
| M94172_s_at | |
| A_32_P153773 | |
| I_2031539 | |
| A_23_P159622 | |
| I_964947 | |
| A_23_P84849 | |
| I_965232 |
| MGI ID | 88296 |
|---|
| GO Molecular Function | voltage-gated ion channel activity |
|---|---|
| ion channel activity | |
| cation channel activity | |
| calcium channel activity | |
| ATP binding | |
| voltage-gated calcium channel activity | |
| calcium ion binding |
| GO ID | GO:0005244 |
|---|---|
| GO:0005216 | |
| GO:0005261 | |
| GO:0005262 | |
| GO:0005524 | |
| GO:0005245 | |
| GO:0005509 | |
| GO:0007626 | |
| GO:0006812 | |
| GO:0008016 | |
| GO:0006811 | |
| GO:0008217 | |
| GO:0006816 | |
| GO:0016020 | |
| GO:0005891 | |
| GO:0016021 | |
| GO:0007268 |
| Swiss-Prot Accession | Q00975 |
|---|
| Keyword | adrenoceptor |
|---|
| OMIM ID | OMIM:601012 |
|---|
| Alias | Cacna1b |
|---|---|
| calcium channel, voltage-dependent, N type, alpha 1B subunit | |
| Cav2.2 | |
| Cchn1a | |
| calcium channel, voltage-dependent, L type, alpha 1B subunit | |
| alpha(1B) | |
| AW060892 | |
| CACNN | |
| calcium channel, N type | |
| calcium channel, voltage-dependent, alpha 1B subunit, N type | |
| Ca-alpha-1B | |
| CACNL1A5 | |
| 4921522D01Rik | |
| BIII | |
| Brain calcium channel III | |
| CACH5 | |
| RIKEN cDNA 4921522D01 gene | |
| Voltage-dependent N-type calcium channel alpha-1B subunit | |
| Calcium channel, L type, alpha-1 polypeptide isoform 5 |
| Organism | Rattus norvegicus |
|---|---|
| Mus musculus | |
| Human |
| LocusLink ID | 257648 |
|---|---|
| 12287 | |
| 99299 | |
| 99310 | |
| 99436 | |
| 774 |
| Source | ResNet |
|---|
| RGD ID | 628852 |
|---|
| Pathway | path |
|---|---|
| path2 | |
| path1 | |
| path3 | |
| path4 | |
| path5 | |
| path6 | |
| path7 | |
| Copy of 'path8' | |
| path8 | |
| pathfeb |
| Unigene ID | Rn.85880 |
|---|---|
| Mm.4424 | |
| Hs.69949 |
| Group | nucleotide binding |
|---|---|
| metal ion binding |