Regulation :

Effect negative
URN urn:agi-Regulation:inout-urn:agi-llid:321:out-urn:agi-llid:351::negative
Nodes APBA2 ---| APP
References 4
Connectivity 2

MedLine Reference 10833507:1010
Sentence Therefore, X11L is thought to play an important role in regulating the amyloidogenic pathway of APP metabolism in neuronal tissues and thus contributing to the pathogenesis of AD .

MedLine Reference 12972431:1217
Sentence This effect is related to the fact that X11L stabilizes APP metabolism (see Fig. 5 ).

MedLine Reference 9890987:1346

MedLine Reference 10777610:2